Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076438 | 1.00 | DRD2 (0.54) | DRD2LSSHTR3ASRD5A1MEN1 | |
| SCHEMBL8038294 | 0.91 | DRD2 (0.49) | DRD2LSSHTR3ASRD5A1MEN1 | |
| SCHEMBL8038298 | 0.91 | DRD2 (0.49) | DRD2LSSHTR3ASRD5A1MEN1 | |
| SCHEMBL8083758 | 0.89 | DRD2 (0.50) | DRD2LSSHTR3ASLC6A3SLC2A1 | |
| SCHEMBL8083754 | 0.89 | DRD2 (0.50) | DRD2LSSHTR3ASLC6A3SLC2A1 | |
| SCHEMBL8089635 | 0.87 | DRD2 (0.49) | DRD2LSSHTR3ASLC2A1 | |
| SCHEMBL8084396 | 0.87 | DRD2 (0.49) | DRD2LSSHTR3ASLC2A1 | |
| SCHEMBL8087998 | 0.87 | DRD2 (0.49) | DRD2LSSHTR3ASLC2A1 | |
| SCHEMBL8087996 | 0.87 | DRD2 (0.49) | DRD2LSSHTR3ASLC2A1 | |
| SCHEMBL8084398 | 0.87 | DRD2 (0.49) | DRD2LSSHTR3ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5641431-A | Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |