Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.79 |
| ▸ | MAOB | P27338 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 3/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SPR | P35270 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Feruloyl Serotonin SCHEMBL30037765 | 0.93 | PTGS2 (0.79) | PTGS2MAOBMEN1KMT2AACHE | |
| N-Feruloyl Serotonin SCHEMBL1809357 | 0.93 | PTGS2 (0.79) | PTGS2MAOBMEN1KMT2AACHE | |
| N-Feruloyl Serotonin SCHEMBL12063415 | 0.93 | PTGS2 (0.79) | PTGS2MAOBMEN1KMT2AACHE | |
| SCHEMBL16414740 | 0.90 | MEN1 (0.87) | PTGS2MAOBMEN1KMT2AACHE | |
| SCHEMBL16414743 | 0.90 | MEN1 (0.87) | PTGS2MAOBMEN1KMT2AACHE | |
| N-Sinapoyl Serotonin SCHEMBL803240 | 0.89 | MAOB (0.74) | PTGS2MAOBMEN1KMT2AACHE | |
| N-Caffeoylserotonin SCHEMBL803616 | 0.88 | PTGS2 (1.00) | PTGS2MAOBMEN1KMT2AACHE | |
| N-Caffeoylserotonin SCHEMBL30039282 | 0.88 | PTGS2 (1.00) | PTGS2MAOBMEN1KMT2AACHE | |
| N-Caffeoylserotonin SCHEMBL4294054 | 0.88 | PTGS2 (1.00) | PTGS2MAOBMEN1KMT2AACHE | |
| N-P-Methoxy Cinnamoyl Serotonin SCHEMBL10071700 | 0.87 | MAOB (0.82) | PTGS2MAOBMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295624-B2 | Amide derivative and whitening agent | AJINOMOTO CO., INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| EP-2412701-B1 | NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT | AJINOMOTO KK (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | PTGS2 2191/4885MAOB 416/4885MEN1 4229/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | PTGS2 2191/4885MAOB 416/4885MEN1 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.