Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034224 | 0.89 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8036295 | 0.88 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9056961 | 0.86 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8034214 | 0.84 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8040633 | 0.83 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7512841 | 0.83 | SLC22A6 (0.59) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8560788 | 0.80 | GRIN2D (0.43) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7509983 | 0.80 | ADH5 (0.42) | — | |
| SCHEMBL8801189 | 0.79 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8912056 | 0.77 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121265-A | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |