Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508489 | 0.88 | CHEK1 (0.51) | PDE4APDE4BPDE4CPDE4DIDH1 | |
| SCHEMBL4978084 | 0.80 | ADORA3 (0.49) | — | |
| SCHEMBL8038375 | 0.80 | GRIA1 (0.46) | — | |
| SCHEMBL7512841 | 0.79 | SLC22A6 (0.59) | — | |
| SCHEMBL8912201 | 0.75 | PGR (0.45) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7269285 | 0.74 | PGR (0.44) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8557394 | 0.73 | GRIA1 (0.55) | — | |
| SCHEMBL7268865 | 0.72 | GRIA1 (0.53) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7268431 | 0.72 | PDE4A (0.58) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8911996 | 0.72 | PGR (0.51) | PGRIDH1CYP3A4BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743945-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2002-03-06 | — | — | EP | claimed |
| US-5741785-A | IMIDAZOLO(1,2-A)QUINOXALINONE COMPOUNDS; ANTIISCHEMIC AGENTS; NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-04-21 | — | — | US | claimed |
| EP-0743945-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-11-27 | — | — | EP | claimed |
| WO-1995021842-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-08-17 | — | — | WO | claimed |
| EP-0743945-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2002-03-06 | — | — | EP | disclosed |
| US-5741785-A | IMIDAZOLO(1,2-A)QUINOXALINONE COMPOUNDS; ANTIISCHEMIC AGENTS; NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-04-21 | — | — | US | disclosed |
| EP-0743945-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021842-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-08-17 | — | — | WO | disclosed |