Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850301 | 0.84 | PDCD1 (0.33) | PSMB8 | |
| SCHEMBL2093340 | 0.77 | PSMB8 (0.36) | PSMB8ALDH1A1 | |
| SCHEMBL10432656 | 0.73 | PSMB8 (0.36) | PSMB8GABRA1GABRB2ALDH1A1 | |
| SCHEMBL11933059 | 0.71 | PSMB8 (0.43) | PSMB8ALDH1A1 | |
| SCHEMBL1850633 | 0.70 | MAPT (0.44) | ALDH1A1 | |
| SCHEMBL29208124 | 0.70 | PRNP (0.34) | PSMB8GABRA1GABRB2ALDH1A1 | |
| SCHEMBL30184539 | 0.70 | PRNP (0.34) | PSMB8GABRA1GABRB2ALDH1A1 | |
| SCHEMBL16442543 | 0.69 | ALDH1A1 (0.44) | PSMB8ALDH1A1 | |
| SCHEMBL2388976 | 0.69 | CNR2 (0.46) | ALDH1A1CNR1CNR2 | |
| SCHEMBL1851331 | 0.69 | GPR35 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060508-A | FOR TREATING URINARY STRESS INCONTINENCE, GASTROINTESTINAL DISORDERS, ULCERS, MIGRAINES | SYNTHELABO (FR) | 2000-05-09 | — | — | US | disclosed |