Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024870 | 0.89 | GCGR (0.44) | GCGRNPSR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8032359 | 0.89 | FABP3 (0.43) | GCGRCNR1NPSR1HPGDTSHR | |
| SCHEMBL4010063 | 0.82 | CNR1 (0.41) | CNR1NPSR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8031430 | 0.79 | CNR2 (0.41) | CNR1NPSR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8027046 | 0.78 | ADORA3 (0.41) | CNR1NPSR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8038540 | 0.78 | GCGR (0.45) | GCGRHPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL8038367 | 0.76 | SMN1; SMN2 (0.40) | NPSR1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL4011470 | 0.75 | FABP3 (0.45) | GCGRNPSR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8032664 | 0.75 | CNR2 (0.42) | NPSR1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL4007725 | 0.74 | ADORA3 (0.39) | GCGRNPSR1HPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |