Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024870 | 0.89 | GCGR (0.44) | GCGRALDH1A1KMT2AADORA3MAPT | |
| SCHEMBL8039244 | 0.86 | HSD17B10 (0.42) | GCGRALDH1A1KMT2ATDP1ADORA3 | |
| SCHEMBL4010057 | 0.86 | DPP4 (0.48) | GCGRDPP4DPP8DPP9ALDH1A1 | |
| SCHEMBL4011273 | 0.81 | ADORA3 (0.38) | GCGRDPP4DPP8DPP9TDP1 | |
| SCHEMBL8038524 | 0.78 | GCGR (0.43) | GCGRALDH1A1KMT2AADORA3MAPT | |
| SCHEMBL8031430 | 0.78 | CNR2 (0.41) | ALDH1A1KMT2ATDP1ADORA3MAPT | |
| SCHEMBL8027046 | 0.78 | ADORA3 (0.41) | ALDH1A1KMT2AADORA3MAPTTP53 | |
| SCHEMBL4010060 | 0.78 | DPP4 (0.36) | GCGRDPP4DPP8DPP9ADORA3 | |
| SCHEMBL8042776 | 0.75 | TSHR (0.48) | ALDH1A1ADORA3MAPTTP53HSD17B10 | |
| SCHEMBL4011470 | 0.74 | FABP3 (0.45) | GCGRDPP4DPP8DPP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |