Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050020 | 0.91 | SMN1; SMN2 (0.33) | POLBALDH1A1L3MBTL1LMNAATM | |
| SCHEMBL8038642 | 0.90 | ALOX15 (0.36) | POLBALDH1A1L3MBTL1LMNAATM | |
| SCHEMBL11938481 | 0.78 | ALDH1A1 (0.39) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL1962459 | 0.78 | ALDH1A1 (0.39) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL12030067 | 0.78 | ALDH1A1 (0.39) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL1964683 | 0.78 | ALDH1A1 (0.39) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL34461866 | 0.76 | ALOX15 (0.39) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL10485886 | 0.76 | ALDH1A1 (0.37) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL11540510 | 0.76 | ALDH1A1 (0.37) | POLBALDH1A1LMNAHSD17B10ATM | |
| SCHEMBL4445787 | 0.74 | PPM1B (0.43) | POLBALDH1A1LMNAHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080750-A | FOR PROPHYLAXIS AND TREATMENT OF DISEASES CAUSED BY INFECTION BY ROTAVIRUS | NIPPON SHOJI KAISHA LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0806418-A2 | Novel pyrimidine compound and anti-rotavirus agent | NIPPON SHOJI KAISHA, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |