Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038682 | 0.90 | POLB (0.35) | ALOX15GAAPOLBL3MBTL1LMNA | |
| SCHEMBL8050020 | 0.85 | SMN1; SMN2 (0.33) | ALOX15GAAPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9065399 | 0.76 | ALOX15 (0.46) | ALOX15GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL4640203 | 0.73 | ALOX15 (0.43) | ALOX15GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL1300428 | 0.72 | ALOX15 (0.41) | ALOX15POLBSMN1; SMN2LMNAATM | |
| SCHEMBL34461866 | 0.71 | ALOX15 (0.39) | ALOX15GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL15958605 | 0.69 | OPRM1 (0.49) | ALOX15POLB | |
| SCHEMBL11938481 | 0.69 | ALDH1A1 (0.39) | ALOX15GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL1964683 | 0.69 | ALDH1A1 (0.39) | ALOX15GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL12030067 | 0.69 | ALDH1A1 (0.39) | ALOX15GAAPOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080750-A | FOR PROPHYLAXIS AND TREATMENT OF DISEASES CAUSED BY INFECTION BY ROTAVIRUS | NIPPON SHOJI KAISHA LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0806418-A2 | Novel pyrimidine compound and anti-rotavirus agent | NIPPON SHOJI KAISHA, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |