Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479270 | 0.84 | FBP1 (0.56) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL7245950 | 0.84 | GLO1 (0.66) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL1856657 | 0.82 | GLO1 (0.66) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL6466353 | 0.82 | FBP1 (0.59) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL18484537 | 0.82 | FBP1 (0.54) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL6466356 | 0.82 | FBP1 (0.59) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL6466349 | 0.82 | FBP1 (0.59) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL1856375 | 0.81 | FBP1 (0.58) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL275826 | 0.81 | ALDH1A1 (0.50) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL7820823 | 0.81 | ALDH1A1 (0.50) | FBP1SMN1; SMN2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | claimed |
| EP-0440324-A2 | Substituted beta-diketones and their use | ORION-YHTYMÀ OY (FI) | 1991-08-07 | — | — | EP | claimed |
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | disclosed |
| US-5292771-A | Treating inflammatory bowel disease | ORION-YHTYMA OY (FI) | 1994-03-08 | — | — | US | disclosed |
| US-5185370-A | Substituted β-diketones and their use | ORION-YHTYMA OY (FI) | 1993-02-09 | — | — | US | disclosed |
| EP-0440324-A2 | Substituted beta-diketones and their use | ORION-YHTYMÀ OY (FI) | 1991-08-07 | — | — | EP | disclosed |