Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038187 | 0.88 | ALDH1A1 (0.54) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL28111184 | 0.86 | THRB (0.48) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL3691364 | 0.83 | THRB (0.46) | THRBTSHRALDH1A1HSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL27808631 | 0.83 | THRB (0.54) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL30775445 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL28338758 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL961984 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL3633964 | 0.81 | THRB (0.45) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL29716499 | 0.81 | THRB (0.55) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL145662 | 0.81 | THRB (0.55) | THRBTSHRALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |