Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043361 | 0.88 | MEN1 (0.33) | MEN1KMT2AL3MBTL1MAPTMAPK1 | |
| SCHEMBL8039021 | 0.83 | RAB9A (0.43) | MEN1KMT2AMAPTRAB9ATDP1 | |
| SCHEMBL7568799 | 0.72 | GRIA1 (0.51) | — | |
| SCHEMBL7567546 | 0.71 | GRIA1 (0.50) | — | |
| SCHEMBL7569263 | 0.71 | GRIA1 (0.50) | — | |
| SCHEMBL7574943 | 0.67 | MEN1 (0.44) | MEN1KMT2AL3MBTL1MAPTMAPK1 | |
| SCHEMBL8037120 | 0.64 | MEN1 (0.47) | MEN1KMT2AL3MBTL1MAPTMAPK1 | |
| SCHEMBL6688963 | 0.64 | CYP3A4 (0.46) | MEN1KMT2AMAPTMAPK1NPSR1 | |
| SCHEMBL21383091 | 0.63 | L3MBTL1 (0.63) | MEN1KMT2AL3MBTL1MAPTMAPK1 | |
| SCHEMBL14941907 | 0.63 | L3MBTL1 (0.60) | MEN1KMT2AL3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |