Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038945 | 0.88 | MEN1 (0.40) | MEN1KMT2AL3MBTL1MAPK1NPSR1 | |
| SCHEMBL8039021 | 0.77 | RAB9A (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL7565679 | 0.77 | GRIA1 (0.46) | — | |
| SCHEMBL8604916 | 0.75 | CFB (0.35) | MEN1KMT2AHTR1AS1PR5MAPT | |
| SCHEMBL8043322 | 0.70 | MEN1 (0.38) | MEN1KMT2AL3MBTL1MAPK1NPSR1 | |
| SCHEMBL8038984 | 0.68 | HTR1A (0.33) | HTR1A | |
| SCHEMBL7569263 | 0.65 | GRIA1 (0.50) | — | |
| SCHEMBL7567546 | 0.65 | GRIA1 (0.50) | — | |
| SCHEMBL7568799 | 0.64 | GRIA1 (0.51) | — | |
| SCHEMBL7565366 | 0.62 | GRIA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |