Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 6/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034915 | 0.91 | MAPT (0.46) | MAPTTMIGD3ADORA3ADORA1GRM5 | |
| SCHEMBL8022999 | 0.90 | MAPT (0.42) | MAPTTMIGD3ADORA3EHMT2EHMT1 | |
| SCHEMBL8038398 | 0.89 | TMIGD3 (0.46) | HDAC1MAPTTMIGD3ADORA3ADORA1 | |
| SCHEMBL8038965 | 0.89 | TMIGD3 (0.50) | MAPTTMIGD3ADORA3ADORA1GRM5 | |
| SCHEMBL28428243 | 0.89 | ADORA3 (0.56) | MAPTTMIGD3ADORA3ADORA1GRM5 | |
| SCHEMBL8038958 | 0.87 | MAPT (0.40) | MAPTTMIGD3ADORA3EHMT2EHMT1 | |
| SCHEMBL8032750 | 0.85 | ADORA3 (0.49) | MAPTTMIGD3ADORA3ADORA1GRM5 | |
| SCHEMBL8021617 | 0.83 | TMIGD3 (0.45) | MAPTTMIGD3ADORA3ADORA1GRM5 | |
| SCHEMBL8039049 | 0.83 | TMIGD3 (0.45) | MAPTTMIGD3ADORA3ADORA1GRM5 | |
| SCHEMBL8038333 | 0.83 | ALDH1A1 (0.53) | MAPTTMIGD3ADORA3GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099177-A1 | AMINO IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |