SCHEMBL8039396

SCHEMBL8039396

CC(N)C=O.CCOC(C)OCC

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.60
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL856006 0.84 LMNA (0.67) LMNATHRB
Isobutyraldehyde SCHEMBL427264 0.84 LMNA (0.67) LMNATHRB
SCHEMBL5618549 0.84 LMNA (0.52) LMNATHRB
SCHEMBL11769218 0.82 LMNA (0.63) LMNATHRB
SCHEMBL11338287 0.82 LMNA (0.63) LMNATHRB
Acetaldehyde SCHEMBL212729 0.81 LMNA (0.71) LMNATHRB
SCHEMBL4293299 0.81 LMNA (0.71) LMNATHRB
SCHEMBL7166170 0.81 LMNA (0.48) LMNA
SCHEMBL9192876 0.80 LMNA (0.60) LMNATHRB
SCHEMBL5582150 0.80 LMNA (0.60) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885877-B1 Process for hydrogenation of cyanopropionaldehyde-containing cyanopropionaldehyde acetals AIR PROD & CHEM (US) 2000-04-12 EP disclosed
US-5886227-A Process for hydrogenation of cyanopropionaldehyde-containing cyanopropionadelhyde acetals AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-03-23 US disclosed
EP-0885877-A1 Process for hydrogenation of cyanopropionaldehyde-containing cyanopropionaldehyde acetals AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-12-23 EP disclosed
US-5847220-A Process for hydrogenation of cyanopropionaldehyde-containing cyanopropionaldehyde acetals AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-12-08 US disclosed
US-5532233-A PLATELET ACTIVATING FACTOR ANTAGONIST BOEHRINGER INGELHEIM KG (DE) 1996-07-02 US disclosed
EP-0019745-A1 2-Aminopropanal acetals, their preparation, fungicidal formulations containing them, their preparation and process for combating fungi BASF Aktiengesellschaft (DE) 1980-12-10 EP disclosed
US-3956297-A 9H-Dibenzo[b,f]imidazo[1,2-d][1,4]diazepines THE UPJOHN COMPANY (US) 1976-05-11 US disclosed