Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851331 | 0.87 | GPR35 (0.60) | GPR35NPSR1RXFP1PRNPPKM | |
| SCHEMBL17204739 | 0.83 | LMNA (0.44) | GPR35PDE10ASMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL1850633 | 0.80 | MAPT (0.44) | SMN1; SMN2NPSR1RXFP1KDM4ELMNA | |
| SCHEMBL31728316 | 0.76 | GPR35 (0.32) | GPR35RXFP1PKMKDM4ELMNA | |
| SCHEMBL1850127 | 0.76 | GPR35 (0.48) | GPR35SMN1; SMN2RXFP1KDM4ELMNA | |
| SCHEMBL10144278 | 0.75 | GPR35 (0.73) | GPR35NPSR1RXFP1PKM | |
| SCHEMBL2093340 | 0.74 | PSMB8 (0.36) | GPR35 | |
| SCHEMBL21950399 | 0.73 | GPR35 (0.44) | GPR35PRNPKMT2A | |
| SCHEMBL2610250 | 0.72 | RXFP1 (0.61) | SMN1; SMN2RXFP1PRNPKDM4ELMNA | |
| SCHEMBL7204195 | 0.71 | MEN1 (0.37) | GPR35RXFP1PRNPKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060508-A | FOR TREATING URINARY STRESS INCONTINENCE, GASTROINTESTINAL DISORDERS, ULCERS, MIGRAINES | SYNTHELABO (FR) | 2000-05-09 | — | — | US | disclosed |
| EP-0923567-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008834-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-03-05 | — | — | WO | disclosed |