Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040104 | 0.87 | KMT2A (0.43) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL8049234 | 0.76 | MAPT (0.39) | PDK2 | |
| SCHEMBL8046733 | 0.76 | MAPT (0.39) | PDK2 | |
| SCHEMBL8053515 | 0.76 | MAPT (0.39) | PDK2 | |
| SCHEMBL8052585 | 0.76 | MAPT (0.39) | PDK2 | |
| SCHEMBL8043998 | 0.75 | MAPT (0.39) | PDK2 | |
| SCHEMBL8052590 | 0.75 | MAPT (0.39) | PDK2 | |
| SCHEMBL8040111 | 0.71 | PTPN11 (0.38) | PDK2PTPN11 | |
| SCHEMBL8046738 | 0.70 | HDAC1 (0.33) | — | |
| SCHEMBL8052434 | 0.70 | HDAC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085978-A1 | BRIDGED CARBOCYCLIC OXIME HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS | ENANTA PHARCEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |