SCHEMBL8040717

SCHEMBL8040717

CC(CO)(CO)C(C=CC(=O)O)(C=CC(=O)O)C=CC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
HCAR2 Q8TDS4 2/20 0.31
GABRR1 P24046 2/20 0.31
GABRR2 P28476 2/20 0.31
BLM P54132 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
LMNA P02545 1/20 0.31
APEX1 P27695 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TBXAS1 P24557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165171 0.80 HCAR2 (0.34) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL18173557 0.80 TSHR (0.33) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL9627725 0.77 TSHR (0.31) TSHRTP53EGLN1EGLN3
SCHEMBL154825 0.76 TSHR (0.38) TSHRTP53EGLN1EGLN3GABRR1
SCHEMBL5705048 0.75 TSHR (0.42) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL334012 0.73 HCAR2 (0.35) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL17451338 0.71 TSHR (0.33) TSHRTP53EGLN1EGLN3GABRR1
SCHEMBL315978 0.71 TSHR (0.33) TSHRTP53EGLN1EGLN3GABRR1
Fumaric Acid SCHEMBL10396296 0.70 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL11308587 0.70 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0279892-B1 Polycarboxylic acids with small amount of residual monomer GOODRICH CO B F (US) 1994-07-13 EP claimed
EP-3137530-B1 CURABLE AQUEOUS POLYURETHANE DISPERSIONS MADE FROM RENEWABLE RESOURCES. ARKEMA FRANCE (FR) 2020-05-27 EP disclosed
EP-3137530-A1 CURABLE AQUEOUS POLYURETHANE DISPERSIONS MADE FROM RENEWABLE RESOURCES. Arkema France (FR) 2017-03-08 EP disclosed
US-20170049684-A1 CURABLE AQUEOUS POLYURETHANE DISPERSIONS MADE FROM RENEWABLE RESOURCES ARKEMA FRANCE (FR) 2017-02-23 US disclosed
WO-2015165902-A1 CURABLE AQUEOUS POLYURETHANE DISPERSIONS MADE FROM RENEWABLE RESOURCES. ARKEMA FRANCE (FR) 2015-11-05 WO disclosed
EP-0762208-B1 Light sensitive composition KONISHIROKU PHOTO IND (JP) 2000-04-12 EP disclosed
US-5773194-A PHOTOSENSITIVITY; DURABILITY KONICA CORPORATION (JP) 1998-06-30 US disclosed
EP-0762208-A2 Light sensitive composition, presensitized lithographic printing plate and image forming method employing the printing plate KONICA CORPORATION (JP) 1997-03-12 EP disclosed
EP-0130193-A1 METHOD AND DEVICE FOR MANUFACTURING A PRINTING IMAGE STORING ELEMENT FOR THE FLAT PRINTING PROCESS Schneider, Josef Dr. (DE) 1985-01-09 EP disclosed
WO-1984002494-A1 METHOD AND DEVICE FOR MANUFACTURING A PRINTING IMAGE STORING ELEMENT FOR THE FLAT PRINTING PROCESS SCHNEIDER JOSEF 1984-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170049684-A1 CURABLE AQUEOUS POLYURETHANE DISPERSIONS MADE FROM RENEWABLE RESOURCES POLR1C, NACA, PRKDC TSHR 4719/4885TP53 1376/4885EGLN1 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.