Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040834 | 0.98 | ACHE (0.41) | ACHELMNAKIF11KMT2ANPC1 | |
| SCHEMBL2383687 | 0.93 | ACHE (0.48) | ACHELMNAKMT2ANPC1RAB9A | |
| SCHEMBL27973529 | 0.91 | ACHE (0.46) | ACHELMNAKMT2ANPC1RAB9A | |
| SCHEMBL8443586 | 0.91 | ACHE (0.46) | ACHELMNAKMT2ANPC1RAB9A | |
| SCHEMBL7771302 | 0.91 | ACHE (0.46) | ACHELMNAKMT2ANPC1RAB9A | |
| SCHEMBL11463261 | 0.91 | ACHE (0.46) | ACHELMNAKMT2ANPC1RAB9A | |
| SCHEMBL10880074 | 0.80 | MEN1 (0.33) | KMT2AESR2MEN1CA1CA2 | |
| SCHEMBL7707561 | 0.79 | MMP3 (0.44) | LMNAKMT2ANPSR1CYP3A4ESR2 | |
| SCHEMBL27275041 | 0.78 | ACHE (0.48) | ACHELMNAKMT2ANPC1RAB9A | |
| SCHEMBL258227 | 0.78 | ACHE (0.48) | ACHELMNAKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438638-B1 | Process for producing norcamphane dicarbonitriles | MITSUI CHEMICALS INC (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5087722-A | Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0438638-A1 | Process for producing norcamphane dicarbonitriles | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-31 | — | — | EP | disclosed |