SCHEMBL258227

SCHEMBL258227

Cc1ccc(OP(O)Oc2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.48
LMNA P02545 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
TEAD4 Q15561 1/20 0.41
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
WDR5 P61964 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
RELA Q04206 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
HPGD P15428 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11311298 0.97 ACHE (0.46) ACHELMNATDP1CYP3A4TSHR
SCHEMBL3874496 0.91 SMN1; SMN2 (0.44) ACHELMNATSHRMAPTMEN1
P-Xylene SCHEMBL28755299 0.88 LMNA (0.43) ACHELMNATSHRMAPTMEN1
SCHEMBL28004434 0.88 ACHE (0.48) ACHELMNATDP1CYP3A4TSHR
SCHEMBL10413331 0.86 ACHE (0.41) ACHELMNATDP1CYP3A4TSHR
SCHEMBL25672828 0.85 RAB9A (0.41) ACHELMNATDP1TEAD4ALDH1A1
SCHEMBL2383687 0.84 ACHE (0.48) ACHELMNATDP1CYP3A4TSHR
SCHEMBL27275041 0.84 ACHE (0.48) ACHELMNATDP1CYP3A4TSHR
Toluene SCHEMBL29211585 0.83 LMNA (0.50) ACHELMNATSHRMEN1KMT2A
SCHEMBL11463261 0.82 ACHE (0.46) ACHELMNATDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 741 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483569-B Polycarbonate antioxidant, preparation method and polycarbonate composition 万华化学集团股份有限公司 2022-02-18 CN claimed
EP-2749629-B1 WORKING FLUID COMPOSITION FOR A REFRIGERATING MACHINE JX NIPPON OIL & ENERGY CORP (JP) 2017-04-26 EP claimed
EP-2749629-A1 Working fluid composition for a refrigerating machine Nippon Oil Corporation (JP) 2014-07-02 EP claimed
US-8193274-B2 Metal-clad laminates having improved peel strength and compositions useful for the preparation thereof ARLON (US) 2012-06-05 US claimed
US-7723276-B2 Oil for cutting and grinding by ultra low volume oil feed system and for sliding surface and method for cutting and grinding by ultra low volume feed system using the oil NIPPON OIL CORPORATION (JP) 2010-05-25 US claimed
EP-4711434-A1 REFRIGERANT CYCLE APPARATUS Daikin Industries, Ltd. (JP) 2026-03-18 EP disclosed
US-12534679-B2 Lubricant base oil and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2026-01-27 US disclosed
US-12529005-B2 Lubricating oil compositions for electric vehicles CHEVRON JAPAN LTD. (JP) 2026-01-20 US disclosed
EP-4234293-B1 REFRIGERATION CYCLE DEVICE FOR VEHICLE DAIKIN IND LTD (JP) 2025-12-24 EP disclosed
US-12441922-B2 Refrigerant-containing composition, use of same, refrigerator having same, operation method for said refrigerator, and refrigeration cycle device equipped with same DAIKIN INDUSTRIES, LTD. (JP) 2025-10-14 US disclosed
EP-4433564-B1 LUBRICATING OIL COMPOSITIONS FOR ELECTRIC VEHICLES CHEVRON JAPAN LTD (JP) 2025-08-27 EP disclosed
EP-4559997-A1 LUBRICATING OIL COMPOSITION ENEOS Corporation (JP) 2025-05-28 EP disclosed
US-4209431-A OXIDATION AND HEAT RESISTANCE WITCO CHEMICAL CORPORATION (US) 1980-06-24 US disclosed
US-4110306-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof ARGUS CHEMICAL CORPORATION (US) 1978-08-29 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4098849-A ALPHA-AMINO PHOSPHONIC ACIDS PETROLITE CORPORATION (US) 1978-07-04 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-4005160-A Preparation of α-amino phosphonic acid derivatives PETROLITE CORPORATION (US) 1977-01-25 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534679-B2 Lubricant base oil and lubricant composition INF2, F2, U2AF2 ACHE 4680/4885LMNA 2333/4885TDP1 942/4885
US-12529005-B2 Lubricating oil compositions for electric vehicles BRSK2, TRIB1, SCO2 ACHE 923/4885LMNA 4340/4885TDP1 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.