Procysteine

Procysteine

SCHEMBL8040939

C1CSCN1.O=C1NC(C(=O)O)CS1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.41
CTH P32929 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Procysteine SCHEMBL1134004 0.83
Procysteine SCHEMBL352387 0.83
Procysteine SCHEMBL83023 0.83
Procysteine SCHEMBL9139321 0.83 HTT (0.53) HTTCTH
Procysteine SCHEMBL8428864 0.81 HTT (0.52) HTTCTH
Procysteine SCHEMBL10623235 0.81 HTT (0.52) HTTCTH
Procysteine SCHEMBL4164380 0.81 HTT (0.52) HTTCTH
Pidolic Acid SCHEMBL5971140 0.75 TPSAB1 (0.35) HTT
Thiazolidine SCHEMBL3821706 0.71
Thiazolidine SCHEMBL7107836 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127165-A NUCLEIC ACID WHICH ENCODES ENZYME HAVING DEFINED AMINO ACID SEQUENCE; USED TO PREPARE GLUTATHIONE ANALOGS AND ANTIBODIES AGAINST ENZYME, DETECT GENE IN ANIMALS, MODIFY ENZYME PRODUCTION, CONSTRUCT MODELS FOR EVALUATION OF THERAPIES CORNELL RESEARCH FOUNDATION, INC. (US) 2000-10-03 US disclosed
EP-0697882-A4 USE OF GLUTATHIONE DIESTERS CORNELL RES FOUNDATION INC (US) 1999-04-07 EP disclosed
US-5869456-A ADMINISTERING TO INCREASE LEVELS OF GLUTATHIONE IN HUMAN CELLS CORNELL RESEARCH FOUNDATION, INC. (US) 1999-02-09 US disclosed
WO-1996025172-A1 RAT GLUTATHIONE SYNTHETASE GENE CORNELL RESEARCH FOUNDATION, INC. (US) 1996-08-22 WO disclosed
EP-0697882-A1 USE OF GLUTATHIONE DIESTERS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-02-28 EP disclosed
WO-1994025052-A1 USE OF GLUTATHIONE DIESTERS CORNELL RESEARCH FOUNDATION, INC. (US) 1994-11-10 WO disclosed
US-4879370-A ALKYL ESTER TO INCREASE CELLULAR LEVELS CORNELL RESEARCH FOUNDATION, INC. (US) 1989-11-07 US disclosed
US-4784685-A MONOALKYL ESTERS OF GLUTATHIONE TO YIELD GLUTATHIONE CORNELL RESEARCH FOUNDATION, INC. (US) 1988-11-15 US disclosed
US-4710489-A ADMINISTERING PURE ALKYL MONOESTERS OF GLUTATHIONE; IN VIVO HYDROLYSIS CORNELL RESEARCH FOUNDATION, INC. (US) 1987-12-01 US disclosed