Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CTH | P32929 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CAD | P27708 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Procysteine SCHEMBL352387 | 0.98 | — | — | |
| Procysteine SCHEMBL83023 | 0.98 | — | — | |
| Procysteine SCHEMBL1134004 | 0.98 | — | — | |
| Procysteine SCHEMBL9139321 | 0.98 | HTT (0.53) | HTTCTHCYP2D6LMNABLM | |
| Procysteine SCHEMBL10623235 | 0.96 | HTT (0.52) | HTTCTHCYP2D6LMNABLM | |
| Procysteine SCHEMBL8428864 | 0.96 | HTT (0.52) | HTTCTHCYP2D6LMNABLM | |
| Procysteine SCHEMBL20822405 | 0.82 | HTT (0.45) | HTTCTHLMNABLMKMT2A | |
| Procysteine SCHEMBL1150486 | 0.82 | HTT (0.45) | HTTCTHGRIA2 | |
| Procysteine SCHEMBL8040939 | 0.81 | HTT (0.41) | HTTCTH | |
| Procysteine SCHEMBL1681501 | 0.79 | PTGS1 (0.47) | HTTCTHCADGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916712-B2 | Compositions and methods for cytoprotection | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-12-23 | — | — | US | disclosed |
| US-20140155365-A1 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-05 | — | — | US | disclosed |
| US-20090042850-A1 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042850-A1 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION | PRDX5, TXN2, GLS | HTT 3806/4885CTH 161/4885CYP2D6 4505/4885 |
| US-20140155365-A1 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION | PRDX5, TXN2, GLS | HTT 3806/4885CTH 161/4885CYP2D6 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.