SCHEMBL8040978

SCHEMBL8040978

CC(C)(C)OC(=O)c1ooc1C(=O)OC1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
HTT P42858 2/20 0.43
MMP9 P14780 3/20 0.40
MMP12 P39900 3/20 0.40
MMP1 P03956 2/20 0.40
MMP2 P08253 2/20 0.39
CYP19A1 P11511 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 3/20 0.38
EPHX1 P07099 2/20 0.37
NPSR1 Q6W5P4 2/20 0.36
POLB P06746 1/20 0.36
STS P08842 3/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043839 0.80 MMP9 (0.41) SMN1; SMN2NPC1RAB9AHTTMMP9
SCHEMBL8039496 0.78 CYP2C9 (0.40) SMN1; SMN2NPSR1MAPTTP53
SCHEMBL11593346 0.73 EPHX1 (0.44) SMN1; SMN2NPC1RAB9AHTTCYP19A1
SCHEMBL11592227 0.73 EPHX1 (0.44) SMN1; SMN2NPC1RAB9AHTTCYP19A1
SCHEMBL11591027 0.73 EPHX1 (0.44) SMN1; SMN2NPC1RAB9AHTTCYP19A1
SCHEMBL11519646 0.73 EPHX1 (0.44) SMN1; SMN2NPC1RAB9AHTTCYP19A1
SCHEMBL11592616 0.73 EPHX1 (0.44) SMN1; SMN2NPC1RAB9AHTTCYP19A1
SCHEMBL4345814 0.71 CYP2C9 (0.40) TSHRALDH1A1NPSR1MAPTMEN1
SCHEMBL8037889 0.71 DGAT1 (0.40) TSHRALDH1A1NPSR1LMNAMAPT
SCHEMBL26635785 0.71 EPHX1 (0.41) SMN1; SMN2NPC1RAB9AHTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127325-A GRAFT COPOLYMER OF AN OIL-SOLUBLE OLEFIN POLYMER AND OF A COPOLYMER (B) OF A MONOMER HAVING A PEROXIDE BOND WITH (METH)ACRYLATE; OR COPOLYMER (C) OF A PEROXIDE CONTAINING MONOMER AND SPECIFIED MONOMERS; NO PHASE SEPARATION NOF CORPORATION (JP) 2000-10-03 US disclosed
EP-0872539-A1 VISCOSITY INDEX IMPROVER, PROCESS FOR PREPARING THE SAME AND LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 1998-10-21 EP disclosed