Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349020 | 0.91 | ALDH1A1 (0.60) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| SCHEMBL6340720 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| SCHEMBL8027783 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| Benzoic Acid SCHEMBL8041305 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| SCHEMBL8041208 | 0.83 | FFAR1 (0.48) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| SCHEMBL8037966 | 0.82 | MEN1 (0.50) | ALDH1A1POLBKDM4EPKMSMN1; SMN2 | |
| SCHEMBL9080159 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10POLBKDM4E | |
| SCHEMBL8037895 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| SCHEMBL8044216 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPK10TSHRHSD17B10POLB | |
| SCHEMBL8027767 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK10TSHRHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-5808144-A | ANTIALLERGENS | TEIJIN LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0806412-A1 | BENZENE DERIVATIVES | TEIJIN LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |