Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038295 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1HPGDLMNA | |
| SCHEMBL6349020 | 0.90 | ALDH1A1 (0.60) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL6348830 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| Benzoic Acid SCHEMBL8041305 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL31324947 | 0.83 | KDM4E (0.74) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL13936057 | 0.83 | KDM4E (0.74) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL6340720 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL8027767 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL8041179 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL6339661 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10MAPK10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |