SCHEMBL8041260

SCHEMBL8041260

FC(F)(F)Oc1ccc(C(CC2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
EPHX1 P07099 1/20 0.42
EPHX2 P34913 1/20 0.42
SLC6A4 P31645 5/20 0.40
SLC6A3 Q01959 5/20 0.40
SLC6A2 P23975 3/20 0.40
CTSS P25774 9/20 0.39
CTSL P07711 8/20 0.39
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39
KMT2A Q03164 1/20 0.39
CTSK P43235 5/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21495045 0.84 EPHX2 (0.46) KDM4EALDH1A1POLBEPHX1EPHX2
SCHEMBL21484760 0.81 KDM4E (0.47) KDM4EALDH1A1POLBEPHX1EPHX2
SCHEMBL8467745 0.75 SLC6A3 (0.64) POLBSLC6A4SLC6A3SLC6A2
SCHEMBL8038720 0.75 SLC6A2 (0.46) ALDH1A1SLC6A4SLC6A3SLC6A2MEN1
SCHEMBL2646825 0.75 KDM4E (0.47) KDM4EALDH1A1POLBEPHX1EPHX2
SCHEMBL3966889 0.75 MEN1 (0.53) KDM4ESLC6A4SLC6A3SLC6A2MEN1
SCHEMBL10453959 0.75 MEN1 (0.53) KDM4ESLC6A4SLC6A3SLC6A2MEN1
SCHEMBL9539598 0.74 SLC6A4 (0.39) ALDH1A1EPHX2SLC6A4SLC6A3MEN1
SCHEMBL9540366 0.72 PDE2A (0.37) KDM4EALDH1A1POLBEPHX1EPHX2
SCHEMBL8042705 0.72 SLC6A3 (0.43) SLC6A4SLC6A3SLC6A2MEN1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728829-B1 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-05-03 EP disclosed
EP-0727473-B1 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-01-12 EP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
US-5698136-A LOW TEMPERATURE COMPATIBILITY, CHEMICAL STABILITY CHISSO CORPORATION (JP) 1997-12-16 US disclosed
EP-0728829-A2 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1996-08-28 EP disclosed
EP-0727473-A2 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-08-21 EP disclosed