Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041260 | 0.84 | KDM4E (0.43) | EPHX2EPHX1KDM4EALDH1A1POLB | |
| SCHEMBL9539598 | 0.81 | SLC6A4 (0.39) | EPHX2ALDH1A1MEN1MITFKMT2A | |
| SCHEMBL2652751 | 0.77 | TRPV3 (0.46) | MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL2652705 | 0.77 | TRPV3 (0.46) | MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL966816 | 0.74 | MEN1 (0.58) | KDM4EMEN1KMT2A | |
| SCHEMBL21484760 | 0.73 | KDM4E (0.47) | EPHX2EPHX1KDM4EALDH1A1POLB | |
| SCHEMBL9540366 | 0.73 | PDE2A (0.37) | EPHX2EPHX1KDM4EALDH1A1POLB | |
| SCHEMBL1565871 | 0.73 | EPHX2 (0.49) | EPHX2EPHX1KDM4EALDH1A1POLB | |
| SCHEMBL9153116 | 0.73 | SLC6A2 (0.42) | POLBMEN1MITFKMT2ASLC6A4 | |
| SCHEMBL9966337 | 0.73 | SLC6A2 (0.42) | POLBMEN1MITFKMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201865-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2019-10-24 | — | — | WO | disclosed |