Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539582 | 0.80 | RPS6KB1 (0.39) | PDE2A | |
| SCHEMBL9539598 | 0.78 | SLC6A4 (0.39) | PDE2AALDH1A1EPHX2SLC6A4 | |
| SCHEMBL9539627 | 0.75 | PDE2A (0.45) | PDE2AALDH1A1POLBEPHX2EPHX1 | |
| SCHEMBL9539646 | 0.74 | SLC6A2 (0.44) | SLC6A4 | |
| SCHEMBL9160756 | 0.74 | PDE2A (0.34) | PDE2AEPHX2 | |
| SCHEMBL9160972 | 0.74 | PDE2A (0.34) | PDE2AEPHX2SLC6A4 | |
| SCHEMBL16861435 | 0.74 | PDE2A (0.44) | PDE2AALDH1A1EPHX2SLC6A4EPHX1 | |
| SCHEMBL21495045 | 0.73 | EPHX2 (0.46) | ALDH1A1KDM4EPOLBEPHX2SLC6A4 | |
| SCHEMBL9158049 | 0.73 | CCR5 (0.32) | PDE2A | |
| SCHEMBL8041260 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EPOLBEPHX2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223536-A | Pyrethroid-like pesticides | FMC CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |