Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052785 | 0.81 | DYRK1A (0.41) | HSD17B10HPGDALDH1A1KDM4ERECQL | |
| SCHEMBL8053771 | 0.80 | DYRK1A (0.36) | HSD17B10HPGDALDH1A1KDM4ERECQL | |
| SCHEMBL8053677 | 0.76 | KDM4E (0.33) | HSD17B10HPGDALDH1A1KDM4ERECQL | |
| SCHEMBL7981341 | 0.71 | ALDH1A1 (0.46) | HSD17B10HPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30165031 | 0.69 | ALDH1A1 (0.39) | HSD17B10HPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7496405 | 0.68 | CA2 (0.33) | HSD17B10HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL8052900 | 0.67 | CHEK1 (0.34) | HSD17B10HPGDALDH1A1KDM4ERECQL | |
| SCHEMBL8056632 | 0.64 | CHEK1 (0.36) | HSD17B10HPGDALDH1A1KDM4ERECQL | |
| SCHEMBL6959399 | 0.63 | HTT (0.46) | HSD17B10ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL2263796 | 0.63 | HTT (0.40) | HSD17B10HPGDALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |