Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585659 | 0.90 | L3MBTL1 (0.47) | L3MBTL1METAP1CTSKPKMALDH1A1 | |
| SCHEMBL3654698 | 0.80 | L3MBTL1 (0.47) | L3MBTL1METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8332495 | 0.80 | METAP1 (0.42) | L3MBTL1METAP1CTSKNTRK1CYP3A4 | |
| SCHEMBL21743808 | 0.80 | L3MBTL1 (0.51) | L3MBTL1CYP3A4HDAC3HDAC1HDAC6 | |
| SCHEMBL3564269 | 0.80 | L3MBTL1 (0.48) | L3MBTL1METAP1CTSKCYP3A4MEN1 | |
| SCHEMBL8053475 | 0.79 | CTSK (0.44) | L3MBTL1METAP1CTSKKMT2A | |
| SCHEMBL8059229 | 0.79 | POLB (0.39) | CTSKNTRK1PKMALDH1A1MEN1 | |
| SCHEMBL8052935 | 0.79 | CTSK (0.44) | L3MBTL1METAP1CTSKKMT2A | |
| SCHEMBL28231828 | 0.77 | L3MBTL1 (0.51) | L3MBTL1METAP1CYP3A4MEN1KMT2A | |
| SCHEMBL8053811 | 0.77 | MAPT (0.42) | CTSKNTRK1PKMALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |