Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053475 | 1.00 | CTSK (0.44) | CTSKGLSKMT2AGPR88KDM4E | |
| SCHEMBL8052672 | 0.88 | CTSK (0.52) | CTSKGLSGPR88KDM4ECTSS | |
| SCHEMBL8059076 | 0.87 | CTSK (0.43) | CTSKGPR88METAP1L3MBTL1CTSS | |
| SCHEMBL8059074 | 0.87 | CTSK (0.43) | CTSKGPR88METAP1L3MBTL1CTSS | |
| SCHEMBL8052778 | 0.86 | CTSK (0.45) | CTSKGPR88CTSSCTSL | |
| SCHEMBL8052712 | 0.86 | CTSK (0.45) | CTSKGPR88CTSSCTSL | |
| SCHEMBL1585659 | 0.84 | L3MBTL1 (0.47) | CTSKKDM4EMETAP1L3MBTL1 | |
| SCHEMBL8052740 | 0.80 | MEN1 (0.42) | CTSKKMT2AGPR88KDM4E | |
| SCHEMBL8053649 | 0.80 | MEN1 (0.42) | CTSKKMT2AGPR88KDM4E | |
| SCHEMBL8041384 | 0.79 | L3MBTL1 (0.43) | CTSKKMT2AMETAP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |