SCHEMBL8041469

SCHEMBL8041469

Cc1ccc(C(=O)O)c(OCc2ccccc2)c1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.63
PTGER1 P34995 2/20 0.51
MCL1 Q07820 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
MAOB P27338 1/20 0.46
BAK1 Q16611 1/20 0.45
ALDH1A1 P00352 1/20 0.45
NR4A1 P22736 1/20 0.45
NR4A2 P43354 1/20 0.45
NR4A3 Q92570 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15726040 0.90 PTGER1 (0.57) PTPN1PTGER1MCL1MAPTTDP1
SCHEMBL19700943 0.87 PTPN1 (0.59) PTPN1PTGER1MCL1MAPTTDP1
SCHEMBL21436784 0.85 PTPN1 (0.58) PTPN1PTGER1MCL1MAPTTDP1
SCHEMBL14472082 0.85 PTGER1 (0.49) PTPN1PTGER1MCL1MAPTTDP1
SCHEMBL3424839 0.85 ALDH1A1 (0.55) PTGER1MCL1MAPTTDP1L3MBTL1
SCHEMBL28349091 0.84 PTPN1 (0.49) PTPN1PTGER1MCL1MAPTTDP1
SCHEMBL1396290 0.83 ALDH1A1 (0.57) PTPN1PTGER1MCL1L3MBTL1SMN1; SMN2
SCHEMBL23190746 0.81 MCL1 (0.48) PTPN1PTGER1MCL1MAPTTDP1
Hydrochloric Acid SCHEMBL18037169 0.81 ALDH1A1 (0.55) PTPN1PTGER1MCL1L3MBTL1SMN1; SMN2
SCHEMBL15726036 0.81 LMNA (0.56) PTPN1PTGER1MCL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0992363-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-04-12 EP disclosed