SCHEMBL8044822

SCHEMBL8044822

C=CC(=O)OC(CC)c1cccc(N)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.41
CPB2 Q96IY4 1/20 0.41
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADRB2 P07550 2/20 0.34
ADRB1 P08588 2/20 0.34
ADRB3 P13945 2/20 0.34
ALDH1A1 P00352 2/20 0.33
THRB P10828 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
FKBP1A P62942 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8041628 0.87 TSHR (0.38) CPN1CPB2TP53CYP3A4THRB
SCHEMBL28193320 0.82 L3MBTL1 (0.47) L3MBTL1KDM4E
SCHEMBL1371364 0.82 THRB (0.41) ALDH1A1THRB
SCHEMBL17844649 0.81 THRB (0.41) ALDH1A1THRB
Acetic Acid SCHEMBL28013205 0.80 THRB (0.40) CYP3A4ALDH1A1THRB
SCHEMBL11024046 0.79 KMT2A (0.43) CYP3A4ALDH1A1L3MBTL1KDM4ESMN1; SMN2
Propionic Acid SCHEMBL28013214 0.78 THRB (0.39) ALDH1A1THRBKDM4E
SCHEMBL5270062 0.78 MEN1 (0.43) TP53CYP3A4ALDH1A1THRBKDM4E
Sulfuric Acid SCHEMBL28055050 0.77 THRB (0.38) ALDH1A1THRBKDM4E
SCHEMBL28013206 0.77 HCAR2 (0.41) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed