Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 4/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041719 | 0.84 | TSHR (0.59) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL8030010 | 0.84 | RXRA (0.47) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL8038572 | 0.83 | NPSR1 (0.44) | NPSR1TSHRHPGDKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL4017566 | 0.80 | NPSR1 (0.49) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL8037053 | 0.77 | KDM4E (0.52) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL4016761 | 0.76 | ATM (0.55) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL8033374 | 0.75 | KDM4E (0.50) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL8040593 | 0.75 | TSHR (0.47) | NPSR1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL4009023 | 0.74 | DPP4 (0.42) | NPSR1TSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28331879 | 0.74 | DHODH (0.52) | NPSR1TSHRHPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |