Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042776 | 0.91 | TSHR (0.48) | TSHRALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL8041719 | 0.89 | TSHR (0.59) | TSHRALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL8030010 | 0.86 | RXRA (0.47) | TSHRALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL8038586 | 0.83 | ALDH1A1 (0.45) | TSHRALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL8040307 | 0.82 | GABRA2 (0.49) | ALDH1A1KDM4ELMNAHPGDMAPT | |
| SCHEMBL8034844 | 0.82 | CASP3 (0.46) | TSHRALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL8040669 | 0.81 | NPSR1 (0.42) | TSHRALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL4009023 | 0.78 | DPP4 (0.42) | TSHRALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL8037266 | 0.77 | GABRA2 (0.45) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL8035080 | 0.76 | TSHR (0.47) | TSHRALDH1A1NPSR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |