Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040593 | 0.89 | TSHR (0.47) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8041730 | 0.84 | NPSR1 (0.59) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8036018 | 0.81 | KDM4E (0.56) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8034443 | 0.80 | TSHR (0.53) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8034096 | 0.80 | KDM4E (0.50) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8039256 | 0.80 | KDM4E (0.50) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL22573316 | 0.79 | KDM4E (0.76) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8042776 | 0.79 | TSHR (0.48) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8035080 | 0.78 | TSHR (0.47) | TSHRKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8024872 | 0.78 | KDM4E (0.48) | TSHRKDM4EALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |