Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041245 | 0.88 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8028327 | 0.84 | POLB (0.37) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8028359 | 0.82 | SMN1; SMN2 (0.35) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8041629 | 0.81 | TDP1 (0.34) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8038341 | 0.77 | SMO (0.38) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8040282 | 0.76 | LRRK2 (0.33) | ERN1 | |
| SCHEMBL8038220 | 0.75 | PPIA (0.42) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8028357 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8040084 | 0.74 | ALDH1A1 (0.33) | MAPTALDH1A1SMN1; SMN2NPSR1GAA | |
| SCHEMBL8025559 | 0.71 | MAPT (0.37) | KMT2AMAPTALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |