Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041763 | 0.88 | MEN1 (0.37) | MAPTMEN1KMT2APOLBRAB9A | |
| SCHEMBL8035603 | 0.82 | RAB9A (0.40) | MAPTMEN1KMT2APOLBRAB9A | |
| SCHEMBL8041249 | 0.80 | TAS1R3 (0.35) | ALDH1A1COMT | |
| SCHEMBL8041271 | 0.79 | COMT (0.35) | MAPTMEN1KMT2APOLBRAB9A | |
| SCHEMBL8035622 | 0.74 | COMT (0.37) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8025492 | 0.72 | PPIA (0.49) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8028327 | 0.71 | POLB (0.37) | MAPTMEN1KMT2APOLBRAB9A | |
| SCHEMBL8035683 | 0.71 | SMYD3 (0.32) | COMT | |
| SCHEMBL8040243 | 0.70 | PPIA (0.47) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8025508 | 0.70 | ALDH1A1 (0.37) | MAPTKMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |