Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041249 | 0.88 | TAS1R3 (0.35) | ALDH1A1TTRDRD2TAS1R3TAS1R1 | |
| SCHEMBL8040084 | 0.84 | ALDH1A1 (0.33) | SMN1; SMN2LMNAALDH1A1LRRK2MAPT | |
| SCHEMBL8025559 | 0.82 | MAPT (0.37) | SMN1; SMN2LMNAALDH1A1LRRK2TTR | |
| SCHEMBL8041763 | 0.82 | MEN1 (0.37) | SMN1; SMN2ALDH1A1ERN1MAPTPOLB | |
| SCHEMBL8028357 | 0.82 | ALDH1A1 (0.41) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8038220 | 0.78 | PPIA (0.42) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8028327 | 0.77 | POLB (0.37) | SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL8034162 | 0.76 | LRRK2 (0.38) | LMNAALDH1A1LRRK2MAPTPTK2 | |
| SCHEMBL8035683 | 0.74 | SMYD3 (0.32) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8028353 | 0.73 | CA1 (0.37) | LMNAALDH1A1ERN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |