SCHEMBL8041764

SCHEMBL8041764

NC=CC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 2/20 0.32
ANPEP P15144 1/20 0.32
ERAP2 Q6P179 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19212109 0.81 FDPS (0.35) LAP3ANPEPERAP2
SCHEMBL2460208 0.71 FDPS (0.31)
SCHEMBL19211983 0.71 FDPS (0.31)
SCHEMBL9956490 0.71 LAP3 (0.32) LAP3
SCHEMBL19211986 0.67 KDM4E (0.32)
SCHEMBL19211988 0.67 KDM4E (0.32)
SCHEMBL2034826 0.65 KDM4E (0.33) LAP3ANPEPERAP2
SCHEMBL1083202 0.63 LAP3 (0.33) LAP3
SCHEMBL5485938 0.63 CA2 (0.35) LAP3ANPEP
Phosphoric Acid SCHEMBL7530834 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6083938-A TREATING BONE DISEASES SELECTED FROM THE GROUP CONSISTING OF OSTEOLYTIC BONE DISEASES DUE TO MALIGNANCY, PAGET'S DISEASE AND PRIMARY AND SECONDARY OSTEOPOROSIS LEIRAS OY (FI) 2000-07-04 US disclosed