Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042982 | 0.94 | KMT2A (0.35) | RAB9AALDH1A1SMN1; SMN2NPC1AGTR1 | |
| SCHEMBL8050861 | 0.91 | MAPT (0.32) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL8032541 | 0.86 | LMNA (0.33) | RECQLKMT2AMEN1MAPT | |
| SCHEMBL8043559 | 0.85 | MAPT (0.34) | ALDH1A1NPC1MAPT | |
| SCHEMBL8048326 | 0.84 | TP53 (0.37) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL8052295 | 0.82 | RAB9A (0.40) | RAB9AALDH1A1SMN1; SMN2NPC1AGTR1 | |
| SCHEMBL8042872 | 0.81 | MAPT (0.33) | ALDH1A1MAPT | |
| SCHEMBL8048153 | 0.80 | MAPT (0.32) | ALDH1A1MAPT | |
| SCHEMBL8033927 | 0.79 | NPSR1 (0.40) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL8048329 | 0.77 | MAPT (0.36) | ALDH1A1SMN1; SMN2AGTR1AGTR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |