Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041866 | 0.84 | HTR3E (0.52) | PTPN11PPARGNPC1ALDH1A1RAB9A | |
| SCHEMBL8041854 | 0.71 | PDK2 (0.42) | PTPN11PDK2 | |
| SCHEMBL7989609 | 0.66 | MEN1 (0.56) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL13165957 | 0.63 | MAPT (0.54) | PTPN11NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL25037329 | 0.63 | KMT2A (0.64) | KMT2A | |
| SCHEMBL10364797 | 0.59 | TGM2 (0.45) | NPC1ALDH1A1RAB9AMEN1GAA | |
| SCHEMBL11796342 | 0.59 | PNLIP (0.55) | PTPN11NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL1979046 | 0.59 | PTPN11 (0.55) | PTPN11NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL12455653 | 0.59 | MAPT (0.51) | PTPN11PPARGNPC1ALDH1A1RAB9A | |
| SCHEMBL14288507 | 0.58 | MAPT (0.72) | PTPN11NPC1ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085978-A1 | BRIDGED CARBOCYCLIC OXIME HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS | ENANTA PHARCEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |