Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038432 | 0.83 | TAS1R3 (0.39) | NT5E | |
| SCHEMBL8040365 | 0.80 | ADORA1 (0.42) | P2RY12PRMT6P2RY2P2RY1P2RY6 | |
| SCHEMBL8045409 | 0.76 | ABL1 (0.46) | P2RY2P2RY6NT5E | |
| SCHEMBL9416275 | 0.76 | P2RY12 (0.40) | P2RY12DNPH1PRMT6 | |
| SCHEMBL9416276 | 0.76 | P2RY12 (0.40) | P2RY12DNPH1PRMT6 | |
| SCHEMBL9416296 | 0.74 | ADORA3 (0.43) | P2RY12DNPH1 | |
| SCHEMBL9416297 | 0.74 | ADORA3 (0.43) | P2RY12DNPH1 | |
| SCHEMBL9416263 | 0.74 | P2RY12 (0.39) | P2RY12DNPH1PRMT6 | |
| SCHEMBL31497736 | 0.74 | ADORA2A (0.40) | P2RY12DNPH1PRMT6 | |
| SCHEMBL9416265 | 0.74 | P2RY12 (0.39) | P2RY12DNPH1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084082-A | SOLID PHASE SYNTHESIS BY ATTACHING BETA-LACTAM HAVING NUCLEOBASE TO SOLID SUPPORT, DEPROTECTING HYDROXY GROUP, REACTING FREE HYDROXYL GROUP WITH BETA-LACTAMTIDE HAVING ACTIVATED PHOSPHITE GROUP, AND OXIDIZING | ISIS PHARMACEUTICALS, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| US-5866691-A | Lactam nucleic acids | ISIS PHARMACEUTICALS, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5554746-A | Lactam nucleic acids | ISIS PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |