Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043257 | 0.91 | KDM4E (0.43) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8051935 | 0.84 | GAA (0.39) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8050181 | 0.83 | KDM4E (0.46) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8048096 | 0.81 | MAPT (0.55) | GAAKDM4ENPSR1L3MBTL1MAPT | |
| SCHEMBL8051082 | 0.80 | TSHR (0.55) | GAAKDM4ENPSR1MAPTHSD17B10 | |
| SCHEMBL8049864 | 0.78 | KDM4E (0.44) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8050192 | 0.78 | HSD17B10 (0.51) | GAAKDM4ENPSR1MAPTHSD17B10 | |
| SCHEMBL8044125 | 0.77 | KDM4E (0.47) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8043226 | 0.77 | ALDH1A1 (0.48) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8045239 | 0.76 | NPSR1 (0.41) | GAAKDM4ENPSR1APOBEC3GL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |