Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042281 | 0.91 | GAA (0.41) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8051935 | 0.87 | GAA (0.39) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8050181 | 0.85 | KDM4E (0.46) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8043226 | 0.82 | ALDH1A1 (0.48) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8049124 | 0.81 | TSHR (0.60) | KDM4EGAANPSR1TSHRHSD17B10 | |
| SCHEMBL8047610 | 0.81 | GAA (0.46) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8044125 | 0.80 | KDM4E (0.47) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8048106 | 0.79 | KDM4E (0.56) | KDM4EGAANPSR1L3MBTL1TSHR | |
| SCHEMBL8045929 | 0.78 | KDM4E (0.44) | KDM4EGAANPSR1APOBEC3GL3MBTL1 | |
| SCHEMBL8042464 | 0.76 | TSHR (0.52) | KDM4EGAANPSR1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |