Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TXN | P10599 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043499 | 0.84 | L3MBTL1 (0.41) | ALDH1A1HSD17B10USP2GAAHPGD | |
| SCHEMBL8045239 | 0.84 | NPSR1 (0.41) | ALDH1A1HSD17B10USP2GAAHPGD | |
| SCHEMBL8042322 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HSD17B10USP2GAAHPGD | |
| SCHEMBL8044973 | 0.84 | PDK1 (0.45) | ALDH1A1GAAMAPTKMT2ALMNA | |
| SCHEMBL8045929 | 0.82 | KDM4E (0.44) | ALDH1A1HSD17B10GAAHPGDMAPT | |
| SCHEMBL8043257 | 0.82 | KDM4E (0.43) | ALDH1A1HSD17B10GAAHPGDMAPT | |
| SCHEMBL8050181 | 0.81 | KDM4E (0.46) | ALDH1A1HSD17B10GAAHPGDMAPT | |
| SCHEMBL8045952 | 0.80 | TSHR (0.59) | ALDH1A1HSD17B10USP2GAAHPGD | |
| SCHEMBL8044125 | 0.80 | KDM4E (0.47) | ALDH1A1HSD17B10GAAHPGDMAPT | |
| SCHEMBL8047161 | 0.79 | ALDH1A1 (0.69) | ALDH1A1HSD17B10USP2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |