SCHEMBL8042385

SCHEMBL8042385

CCc1c(C)c(C)cc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.45
CYP2A6 P11509 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HTR2A P28223 1/20 0.45
TSHR P16473 1/20 0.42
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
NCEH1 Q6PIU2 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743898 0.86 CYP1A2 (0.47) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL23846030 0.85 CYP2A6 (0.38) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL2127621 0.85 ALDH1A1 (0.47) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL7915027 0.84 CYP1A2 (0.45) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL2126066 0.83 NCEH1 (0.43) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL28428509 0.82 L3MBTL1 (0.64) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL814436 0.82 CYP1A2 (0.44) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL28778816 0.82 L3MBTL1 (0.48) CYP1A2CYP2A6L3MBTL1HTR2ATSHR
SCHEMBL2128292 0.82 MAPT (0.48) CYP1A2CYP2A6L3MBTL1HTR2AALDH1A1
SCHEMBL30992096 0.81 HTR2A (0.60) CYP1A2CYP2A6L3MBTL1HTR2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5254766-A Alkylation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-19 US claimed
EP-0989179-A1 Refrigerating machine oil Nippon Mitsubishi Oil Corporation (JP) 2000-03-29 EP disclosed
EP-0599448-B1 Solvant for use in carbonless paper, comprising diisopropylmethylnaphthalene, and products utilising same KOCH IND INC (US) 1998-04-29 EP disclosed
EP-0481360-B1 Process for producing alkyl-substituted aromatic hydrocarbon MITSUI PETROCHEMICAL IND (JP) 1997-01-15 EP disclosed
US-5489332-A MIXTURE KOCH INDUSTRIES, INC. (US) 1996-02-06 US disclosed
CN-1029611-C Process for producing alkyl-substituted aromatic hydrocarbons MITSUI PETROCHEMICAL IND (JP) 1995-08-30 CN disclosed
US-5385879-A Carbonless paper solvent comprising diisopropylmethylnaphthalene and products utilizing same KOCH INDUSTRIES, INC. (US) 1995-01-31 US disclosed
EP-0599448-A2 Solvant for use in carbonless paper, comprising diisopropylmethylnaphthalene, and products utilising same KOCH INDUSTRIES, INC. (US) 1994-06-01 EP disclosed
US-5254766-A Alkylation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-19 US disclosed
CN-1060833-A The production method of alkyl-substituted aromatic hydrocarbon MITSUI PETROCHEMICAL IND (JP) 1992-05-06 CN disclosed
EP-0481360-A2 Process for producing alkyl-substituted aromatic hydrocarbon MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-22 EP disclosed
US-4003589-A MICROCAPSULES OF NAPHTHALENE SOLVENT AND DYES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-01-18 US disclosed