Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042385 | 0.82 | CYP1A2 (0.45) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL7915027 | 0.82 | CYP1A2 (0.45) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL28428509 | 0.81 | L3MBTL1 (0.64) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL7195959 | 0.80 | CYP1A2 (0.40) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL2127621 | 0.79 | ALDH1A1 (0.47) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL1169916 | 0.79 | HTR2A (0.60) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL10726277 | 0.78 | APOBEC3A (0.47) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL6548197 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL20562855 | 0.78 | HTR2A (0.50) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR | |
| SCHEMBL2126066 | 0.78 | NCEH1 (0.43) | CYP1A2CYP2A6L3MBTL1HTR2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289710-B1 | Pneumatic tire | BRIDGESTONE CORP (JP) | 2018-11-07 | — | — | EP | disclosed |
| EP-1297974-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-8183327-B2 | Rubber composition for tire and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8058357-B2 | Vulcanizable compositions and tire treads prepared therewith | BRIDGESTONE CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20110071253-A1 | RUBBER COMPOSITION FOR TIRE AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
| EP-2289710-A2 | Pneumatic tire | Bridgestone Corporation (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2287015-A2 | Pneumatic tire | Bridgestone Corporation (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20100000639-A1 | VULCANIZABLE COMPOSITIONS AND TIRE TREADS PREPARED THEREWITH | BRIDGESTONE CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20060272760-A1 | Pneumatic tire | BRIDGESTONE CORPORATION | 2006-12-07 | — | — | US | disclosed |
| US-20030088023-A1 | Containing an alkylenebis(dithio-nitrogen cap) compound, a citraconimide compound, or an acrylate compound; suitable particularly for a reinforcing rubber for tire sidewall portions and for a tire bead filler rubber. | BRIDGESTONE CORPORATION (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-1297974-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20030015272-A1 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| US-20020103089-A1 | Lubricant composition for steel filament and rubber-steel filament composite body | BRIDGESTONE CORPORATION | 2002-08-01 | — | — | US | disclosed |
| EP-1197518-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE WITH THE SAME | BRIDGESTONE CORPORATION (JP) | 2002-04-17 | — | — | EP | disclosed |
| EP-1172430-A2 | Lubricant composition for steel filament and rubber-steel filament composite body | Bridgestone Corporation (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |