Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | AHR | P35869 | 4/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557099 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EMAPTL3MBTL1NOTUM | |
| SCHEMBL972899 | 0.79 | MGAM (0.60) | ALDH1A1KDM4EMEN1KMT2ANOTUM | |
| SCHEMBL8032696 | 0.78 | MAPT (0.71) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL20341649 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTL3MBTL1AHR | |
| SCHEMBL8042130 | 0.76 | HSD17B1 (0.46) | ALDH1A1KDM4EGUSBMEN1KMT2A | |
| SCHEMBL14557095 | 0.75 | SNCA (0.37) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL8043402 | 0.75 | CYP19A1 (0.41) | ALDH1A1KDM4EMAPTL3MBTL1NOTUM | |
| SCHEMBL9179420 | 0.74 | SNCA (0.75) | MAPTGUSBSNCAALOX5 | |
| SCHEMBL970590 | 0.74 | MEN1 (0.46) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL8042639 | 0.73 | PIK3CD (0.43) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |