Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP14 | P54578 | 8/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052277 | 0.90 | HRH3 (0.44) | HRH3CYP2D6KCNH2USP14USP5 | |
| SCHEMBL8686413 | 0.87 | MEN1 (0.43) | HRH3CYP2D6MEN1RAB9AKMT2A | |
| SCHEMBL8044020 | 0.83 | ITGB3 (0.55) | HRH3MEN1RAB9AKMT2A | |
| SCHEMBL8688203 | 0.83 | USP14 (0.44) | MEN1RAB9AKMT2AUSP14USP5 | |
| Hydrochloric Acid SCHEMBL8034450 | 0.83 | ALOX15 (0.56) | HRH3MEN1RAB9AKMT2A | |
| SCHEMBL8686692 | 0.82 | USP14 (0.41) | MEN1RAB9AKMT2AUSP14USP5 | |
| SCHEMBL8044034 | 0.82 | ITGB3 (0.42) | HRH3KCNH2MEN1RAB9AKMT2A | |
| SCHEMBL8043652 | 0.81 | ITGB3 (0.41) | HRH3KCNH2MEN1RAB9AKMT2A | |
| SCHEMBL8043708 | 0.81 | ITGB3 (0.41) | HRH3KCNH2MEN1RAB9AKMT2A | |
| SCHEMBL7273978 | 0.74 | KMT2A (0.48) | HRH3MEN1RAB9AKMT2AUSP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5773442-A | EXHIBIT GPIIB/IIIA RECEPTOR ANTAGONISTIC ACTIVITY; USEFUL FOR THE TREATMENT AND PROPHYLAXIS OF VASCULAR SYSTEM DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0810215-A1 | NOVEL BENZAMIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-03 | — | — | EP | disclosed |